2023
The mammalian midbody and midbody remnant are assembly sites for RNA and localized translation.
Park S, Dahn R, Kurt E, Presle A, VanDenHeuvel K, Moravec C, Jambhekar A, Olukoga O, Shepherd J, Echard A, Blower M, Skop AR. Dev Cell. 2023 Aug 1:S1534-5807(23)00357-X. doi: 10.1016/j.devcel.2023.07.009.
2022
Direct coculture of human pluripotent stem cell-derived cardiac progenitor cells with epicardial cells induces cardiomyocyte proliferation and reduces sarcomere organization.
Floy ME, Dunn KK, Mateyka TD, Reichardt IM, Steinberg AB, Palecek SP. J Mol Cell Cardiol. 2022 Jan;162:144-157.
Proteomic characterization of isolated Arabidopsis clathrin-coated vesicles reveals evolutionarily conserved and plant-specific components.
Dahhan DA, Reynolds GD, Cárdenas JJ, Eeckhout D, Johnson A, Yperman K, Kaufmann WA, Vang N, Yan X, Hwang I, Heese A, De Jaeger G, Friml J, Van Damme D, Pan J, Bednarek SY. Plant Cell. 2022 May 24;34(6):2150-2173
Autophagy Protects against Eosinophil Cytolysis and Release of DNA.
Esnault S, Fichtinger PS, Barretto KT, Fogerty FJ, Bernau K, Mosher DF, Mathur SK, Sandbo N, Jarjour NN. Cells. 2022 Jun 2;11(11):1821.
2021
Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells.
Gastfriend BD, Nishihara H, Canfield SG, Foreman KL, Engelhardt B, Palecek SP, Shusta EV. Elife. 2021 Nov 10;10:e70992.
Beta Cell Dedifferentiation Induced by IRE1α Deletion Prevents Type 1 Diabetes.
Lee H, Lee YS, Harenda Q, Pietrzak S, Oktay HZ, Schreiber S, Liao Y, Sonthalia S, Ciecko AE, Chen YG, Keles S, Sridharan R, Engin F. Cell Metab. 2020 Apr 7;31(4):822-836.e5. doi: 10.1016/j.cmet.2020.03.002.
Keratin 13 deficiency causes white sponge nevus in mice.
Simonson L, Vold S, Mowers C, Massey RJ, Ong IM, Longley BJ, Chang H. Dev Biol. 2020 Dec 1;468(1-2):146-153.
2020
Eosinophil cytolysis on Immunoglobulin G is associated with microtubule formation and suppression of rho-associated protein kinase signalling.
Esnault S, Leet JP, Johansson MW, Barretto KT, Fichtinger PS, Fogerty FJ, Bernau K, Mathur SK, Mosher DF, Sandbo N, Jarjour NN. Clin Exp Allergy. 2020 Feb;50(2):198-212. Epub 2019 Dec 9. doi: 10.1111/cea.13538. PMID: 31750580
Transcriptional Profiling of Primate Central Nucleus of the Amygdala Neurons to Understand the Molecular Underpinnings of Early-Life Anxious Temperament.
Kovner R, Souaiaia T, Fox AS, French DA, Goss CE, Roseboom PH, Oler JA, Riedel MK, Fekete EM, Fudge JL, Knowles JA, Kalin NH. Biol Psychiatry. 2020 Oct 15;88(8):638-648. Epub 2020 May 19. doi: 10.1016/j.biopsych.2020.05.009. PMID: 32709417
Establishment of chromatin accessibility by the conserved transcription factor Grainy head is developmentally regulated.
Nevil M, Gibson TJ, Bartolutti C, Iyengar A, Harrison MM. Development. 2020 Mar 11;147(5):dev185009. doi: 10.1242/dev.185009. PMID: 32098765
Tractions and stress fibers control cell shape and rearrangements in collective cell migration.
Saraswathibhatla, A., Notbohm, J. Phys. Rev. X. 2020 10, 011016. 23 Jan. arXiv:1901.10018 [physics] 2019. doi: https://journals.aps.org/prx/abstract/10.1103/PhysRevX.10.011016
2019
Acetyl-CoA flux regulates the proteome and acetyl-proteome to maintain intracellular metabolic crosstalk.
Dieterich IA, Lawton AJ, Peng Y, Yu Q, Rhoads TW, Overmyer KA, Cui Y, Armstrong EA, Howell PR, Burhans MS, Li L, Denu JM, Coon JJ, Anderson RM, Puglielli L. Nat Commun. 2019 Sep 2;10(1):3929. doi: 10.1038/s41467-019-11945-9. PMID: 31477734
A Tmc1 mutation reduces calcium permeability and expression of mechanoelectrical transduction channels in cochlear hair cells.
Beurg M, Barlow A, Furness DN, Fettiplace R. Proc Natl Acad Sci U S A. 2019 Oct 8;116(41):20743-20749. Epub 2019 Sep 23. doi: 10.1073/pnas.1908058116. PMID: 31548403
Club Cell TRPV4 Serves as a Damage Sensor Driving Lung Allergic Inflammation.
Wiesner DL, Merkhofer RM, Ober C, Kujoth GC, Niu M, Keller NP, Gern JE, Brockman-Schneider RA, Evans MD, Jackson DJ, Warner T, Jarjour NN, Esnault SJ, Feldman MB, Freeman M, Mou H, Vyas JM, Klein BS. Cell Host Microbe. 2020 Apr 8;27(4):614-628.e6. Epub 2020 Mar 3. doi: 10.1016/j.chom.2020.02.006. PMID: 32130954
Coculture of Endothelial Cells with Human Pluripotent Stem Cell-Derived Cardiac Progenitors Reveals a Differentiation Stage-Specific Enhancement of Cardiomyocyte Maturation.
Dunn KK, Reichardt IM, Simmons AD, Jin G, Floy ME, Hoon KM, Palecek SP. Biotechnol J. 2019 Aug;14(8):e1800725. Epub 2019 May 14. doi: 10.1002/biot.201800725. PMID: 30927511
Antigen structure affects cellular routing through DC-SIGN.
Jarvis CM, Zwick DB, Grim JC, Alam MM, Prost LR, Gardiner JC, Park S, Zimdars LL, Sherer NM, Kiessling LL. Proc Natl Acad Sci U S A. 2019 Jul 23;116(30):14862-14867. Epub 2019 Jul 3. doi: 10.1073/pnas.1820165116. PMID: 31270240
CADPS functional mutations in patients with bipolar disorder increase the sensitivity to stress.
Sitbon J, Nestvogel D, Kappeler C, Nicolas A, Maciuba S, Henrion A, Troudet R, Courtois E, Grannec G, Latapie V, Barau C, Le Corvoisier P, Pietrancosta N, Henry C, Leboyer M, Etain B, Nosten-Bertrand M, Martin TFJ, Rhee J, Jamain S. Mol Psychiatry. 2022 Feb 15. Online ahead of print. doi: 10.1038/s41380-021-01151-9. PMID: 35169262
Endogenous Tagging Reveals Differential Regulation of Ca2+ Channels at Single Active Zones during Presynaptic Homeostatic Potentiation and Depression.
Gratz SJ, Goel P, Bruckner JJ, Hernandez RX, Khateeb K, Macleod GT, Dickman D, O’Connor-Giles KM. J Neurosci. 2019 Mar 27;39(13):2416-2429. Epub 2019 Jan 28. doi: 10.1523/JNEUROSCI.3068-18.2019. PMID: 30692227
Human pluripotent stem cell-derived brain pericyte-like cells induce blood-brain barrier properties.
Stebbins MJ, Gastfriend BD, Canfield SG, Lee MS, Richards D, Faubion MG, Li WJ, Daneman R, Palecek SP, Shusta EV. Sci Adv. 2019 Mar 13;5(3):eaau7375. eCollection 2019 Mar. doi: 10.1126/sciadv.aau7375. PMID: 30891496
Continued Activity of the Pioneer Factor Zelda Is Required to Drive Zygotic Genome Activation.
McDaniel SL, Gibson TJ, Schulz KN, Fernandez Garcia M, Nevil M, Jain SU, Lewis PW, Zaret KS, Harrison MM. Mol Cell. 2019 Apr 4;74(1):185-195.e4. Epub 2019 Feb 20. doi: 10.1016/j.molcel.2019.01.014. PMID: 30797686
Optogenetic Inactivation of Transcription Factors in the Early Embryo of Drosophila.
McDaniel SL, Harrison MM. Bio Protoc. 2019 Jul 5;9(13):e3296. eCollection 2019 Jul 5. doi: 10.21769/BioProtoc.3296. PMID: 33654809
2018
Increased transport of acetyl-CoA into the endoplasmic reticulum causes a progeria-like phenotype.
Peng Y, Shapiro SL, Banduseela VC, Dieterich IA, Hewitt KJ, Bresnick EH, Kong G, Zhang J, Schueler KL, Keller MP, Attie AD, Hacker TA, Sullivan R, Kielar-Grevstad E, Arriola Apelo SI, Lamming DW, Anderson RM, Puglielli L. Aging Cell. 2018 Oct;17(5):e12820. Epub 2018 Jul 27. doi: 10.1111/acel.12820. PMID: 30051577
Precise protein localization in dissected Drosophila larvae by correlative light and transmission electron microscopy.
Zhan H, Kielar-Grevstad E, O’Connor-Giles K. 2018 Microscopy and Microanalysis 24 (S1), 1372-1373. Published online by Cambridge University Press. doi: https://doi.org/10.1017/S1431927618007341
Imaging mycobacterial growth and division with a fluorogenic probe.
Hodges HL, Brown RA, Crooks JA, Weibel DB, Kiessling LL. Proc Natl Acad Sci U S A. 2018 May 15;115(20):5271-5276. Epub 2018 Apr 27. doi: 10.1073/pnas.1720996115. PMID: 29703753
Small molecules that inhibit the late stage of Munc13-4-dependent secretory granule exocytosis in mast cells.
Bruinsma S, James DJ, Quintana Serrano M, Esquibel J, Woo SS, Kielar-Grevstad E, Crummy E, Qurashi R, Kowalchyk JA, Martin TFJ. J Biol Chem. 2018 May 25;293(21):8217-8229. Epub 2018 Apr 3. doi: 10.1074/jbc.RA117.001547. PMID: 29615494
Studying the Symbiotic Bacterium Xenorhabdus nematophila in Individual, Living Steinernema carpocapsae Nematodes Using Microfluidic Systems.
Stilwell MD, Cao M, Goodrich-Blair H, Weibel DB. mSphere. 2018 Jan 3;3(1):e00530-17. eCollection 2018 Jan-Feb. doi: 10.1128/mSphere.00530-17. PMID: 29299529
Human angiogenin is a potent cytotoxin in the absence of ribonuclease inhibitor.
Thomas SP, Hoang TT, Ressler VT, Raines RT. RNA. 2018 Aug;24(8):1018-1027. Epub 2018 May 10. doi: 10.1261/rna.065516.117. PMID: 29748193
A Ca2+-stimulated exosome release pathway in cancer cells is regulated by Munc13-4.
Messenger SW, Woo SS, Sun Z, Martin TFJ. J Cell Biol. 2018 Aug 6;217(8):2877-2890. Epub 2018 Jun 21. doi: 10.1083/jcb.201710132. PMID: 29930202
Myeloid-derived growth factor is a resident endoplasmic reticulum protein.
Bortnov V, Annis DS, Fogerty FJ, Barretto KT, Turton KB, Mosher DF. J Biol Chem. 2018 Aug 24;293(34):13166-13175. Epub 2018 Jun 28. doi: 10.1074/jbc.AC118.002052. PMID: 29954947
Expression of novel “LOCGEF” isoforms of ARHGEF18 in eosinophils.
Turton KB, Wilkerson EM, Hebert AS, Fogerty FJ, Schira HM, Botros FE, Coon JJ, Mosher DF. J Leukoc Biol. 2018 Jul;104(1):135-145. Epub 2018 Mar 30. doi: 10.1002/JLB.2MA1017-418RR. PMID: 29601110
Cytosolic Uptake of Large Monofunctionalized Dextrans.
Chyan W, Kilgore HR, Raines RT. Bioconjug Chem. 2018 Jun 20;29(6):1942-1949. Epub 2018 Apr 25. doi: 10.1021/acs.bioconjchem.8b00198. PMID: 29649361
Islet proteomics reveals genetic variation in dopamine production resulting in altered insulin secretion.
Mitok KA, Freiberger EC, Schueler KL, Rabaglia ME, Stapleton DS, Kwiecien NW, Malec PA, Hebert AS, Broman AT, Kennedy RT, Keller MP, Coon JJ, Attie AD. J Biol Chem. 2018 Apr 20;293(16):5860-5877. Epub 2018 Mar 1. doi:
10.1074/jbc.RA117.001102. PMID: 29496998
Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.
Hernández-Santos N, Wiesner DL, Fites JS, McDermott AJ, Warner T, Wüthrich M, Klein BS. Cell Host Microbe. 2018 Apr 11;23(4):511-522.e5. Epub 2018 Mar 22. doi: 10.1016/j.chom.2018.02.011. PMID: 29576482
Characterization of Siglec-8 Expression on Lavage Cells after Segmental Lung Allergen Challenge.
Johansson, M. W., Kelly, E. A., Nguyen, C. L., Jarjour, N. N. , Bochner, B. S. Int Arch Allergy Immunol. 2018 177(1):16-28. Epub 2018 Jun 7. doi: 10.1159/000488951 PMID: 29879704
2017
A conserved maternal-specific repressive domain in Zelda revealed by Cas9-mediated mutagenesis in Drosophila melanogaster.
Hamm DC, Larson ED, Nevil M, Marshall KE, Bondra ER, Harrison MM. 2017 PLoS Genet Dec 19;13(12):e1007120. doi: 10.1371/journal.pgen.1007120. eCollection 2017 PMID: 29261646
Alterations of intrinsic tongue muscle properties with aging.
Cullins MJ, Connor NP. Muscle Nerve. 2017 Dec;56(6):E119-E125. doi: 10.1002/mus.25605. Epub 2017 Mar 10. PMID: 28181263 [PubMed – indexed for MEDLINE]
Properties of acid gels made from sodium caseinate-maltodextrin conjugates prepared by a wet heating method.
Zhang S, Gong Y, Khanal S, Lu Y, Lucey JA. J Dairy Sci. 2017 Nov;100(11):8744-8753. doi: 10.3168/jds.2017-12602. Epub 2017 Sep 6. PMID: 28888602
Monitoring of Dual CRISPR/Cas9-Mediated Steroidogenic Acute Regulatory Protein Gene Deletion and Cholesterol Accumulation Using High-Resolution Fluorescence In Situ Hybridization in a Single Cell.
Lee J, Jefcoate C. Front Endocrinol (Lausanne). 2017 Oct 25;8:289. doi: 10.3389/fendo.2017.00289. eCollection 2017. PMID: 29118738
Cytosolic Delivery of Proteins by Bioreversible Esterification.
Mix KA, Lomax JE, Raines RT. J Am Chem Soc. 2017 Oct 18;139(41):14396-14398. doi: 10.1021/jacs.7b06597. Epub 2017 Oct 10. PMID: 28976737
IL-5-stimulated eosinophils adherent to periostin undergo stereotypic morphological changes and ADAM8-dependent migration.
Johansson MW, Khanna M, Bortnov V, Annis DS, Nguyen CL, Mosher DF. Clin Exp Allergy. 2017 Oct;47(10):1263-1274. doi: 10.1111/cea.12934. Epub 2017 May 5. PMID: 28378503
SCD1 and SCD2 Form a Complex That Functions with the Exocyst and RabE1 in Exocytosis and Cytokinesis.
Mayers JR, Hu T, Wang C, Cárdenas JJ, Tan Y, Pan J, Bednarek SY. Plant Cell. 2017 Oct;29(10):2610-2625. doi: 10.1105/tpc.17.00409. Epub 2017 Sep 29. PMID: 28970336
Kaposi’s sarcoma-associated herpesvirus stably clusters its genomes across generations to maintain itself extrachromosomally.
Chiu YF, Sugden AU, Fox K, Hayes M, Sugden B. J Cell Biol. 2017 Sep 4;216(9):2745-2758. doi: 10.1083/jcb.201702013. Epub 2017 Jul 10. PMID: 28696226 [PubMed – indexed for MEDLINE]
BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells.
Zhang X, Jiang S, Mitok KA, Li L, Attie AD, Martin TFJ. J Cell Biol. 2017 Jul 3;216(7):2151-2166. doi: 10.1083/jcb.201702099. Epub 2017 Jun 16. PMID: 28626000 [PubMed – indexed for MEDLINE]
Electronic and Steric Optimization of Fluorogenic Probes for Biomolecular Imaging.
Chyan W, Kilgore HR, Gold B, Raines RT. J Org Chem. 2017 Apr 21;82(8):4297-4304. Epub 2017 Apr 11. doi: 10.1021/acs.joc.7b00285. PMID: 28345343
STELLA collaborates in distinct mesendodermal cell subpopulations at the fetal-placental interface in the mouse gastrula.
Wolfe AD, Rodriguez AM, Downs KM. Dev Biol. 2017 May 1;425(1):44-57. doi: 10.1016/j.ydbio.2017.03.014. Epub 2017 Mar 18. PMID: 28322735 [PubMed – indexed for MEDLINE]
Munc13-4 functions as a Ca2+ sensor for homotypic secretory granule fusion to generate endosomal exocytic vacuoles.
Woo SS, James DJ, Martin TF. Mol Biol Cell. 2017 Mar 15;28(6):792-808. doi: 10.1091/mbc.E16-08-0617. Epub 2017 Jan 18. PMID: 28100639 [PubMed – indexed for MEDLINE]
Subcellular Localization of HIV-1 gag-pol mRNAs Regulates Sites of Virion Assembly.
Becker JT, Sherer NM. J Virol. 2017 Feb 28;91(6). pii: e02315-16. doi: 10.1128/JVI.02315-16. Print 2017 Mar 15. PMID: 28053097 [PubMed – indexed for MEDLINE]
Molecular basis for the autonomous promotion of cell proliferation by angiogenin.
Hoang TT, Raines RT. Nucleic Acids Res. 2017 Jan 25;45(2):818-831. doi: 10.1093/nar/gkw1192. Epub 2016 Dec 2. PMID: 27915233 [PubMed – indexed for MEDLINE]
The receptor tyrosine kinase AXL mediates nuclear translocation of the epidermal growth factor receptor.
Brand TM, Iida M, Corrigan KL, Braverman CM, Coan JP, Flanigan BG, Stein AP, Salgia R, Rolff J, Kimple RJ, Wheeler DL. Sci Signal. 2017 Jan 3;10(460). pii: eaag1064. doi: 10.1126/scisignal.aag1064. PMID: 28049763 [PubMed – indexed for MEDLINE]
2016
Fife organizes synaptic vesicles and calcium channels for high-probability neurotransmitter release.
Bruckner JJ, Zhan H, Gratz SJ, Rao M, Ukken F, Zilberg G, O’Connor-Giles KM. J Cell Biol. 2017 Jan 2;216(1):231-246. doi: 10.1083/jcb.201601098. Epub 2016 Dec 20. PMID: 27998991 [PubMed – indexed for MEDLINE]
The Transcription Factor Nfatc2 Regulates β-Cell Proliferation and Genes Associated with Type 2 Diabetes in Mouse and Human Islets.
Keller MP, Paul PK, Rabaglia ME, Stapleton DS, Schueler KL, Broman AT, Ye SI, Leng N, Brandon CJ, Neto EC, Plaisier CL, Simonett SP, Kebede MA, Sheynkman GM, Klein MA, Baliga NS, Smith LM, Broman KW, Yandell BS, Kendziorski C, Attie AD. PLoS Genet. 2016 Dec 9;12(12):e1006466. doi: 10.1371/journal.pgen.1006466. eCollection 2016 Dec. PMID: 27935966 [PubMed – indexed for MEDLINE]
Histone chaperone ASF1B promotes human β-cell proliferation via recruitment of histone H3.3.
Paul PK, Rabaglia ME, Wang CY, Stapleton DS, Leng N, Kendziorski C, Lewis PW, Keller MP, Attie AD. Cell Cycle. 2016 Dec;15(23):3191-3202. Epub 2016 Oct 18. PMID: 27753532 [PubMed – indexed for MEDLINE]
Lytic transglycosylases LtgA and LtgD perform distinct roles in remodeling, recycling and releasing peptidoglycan in Neisseria gonorrhoeae.
Schaub RE, Chan YA, Lee M, Hesek D, Mobashery S, Dillard JP. Mol Microbiol. 2016 Dec;102(5):865-881. doi: 10.1111/mmi.13496. Epub 2016 Sep 26. PMID: 27608412 [PubMed – indexed for MEDLINE]
Mouse Tmem135 mutation reveals a mechanism involving mitochondrial dynamics that leads to age-dependent retinal pathologies.
Lee WH, Higuchi H, Ikeda S, Macke EL, Takimoto T, Pattnaik BR, Liu C, Chu LF, Siepka SM, Krentz KJ, Rubinstein CD, Kalejta RF, Thomson JA, Mullins RF, Takahashi JS, Pinto LH, Ikeda A. Elife. 2016 Nov 15;5. pii: e19264. doi: 10.7554/eLife.19264. PMID: 27863209 [PubMed – indexed for MEDLINE]
Analysis of specific RNA in cultured cells through quantitative integration of q-PCR and N-SIM single cell FISH images: Application to hormonal stimulation of StAR transcription.
Lee J, Foong YH, Musaitif I, Tong T, Jefcoate C. Mol Cell Endocrinol. 2016 Jul 5;429:93-105. doi: 10.1016/j.mce.2016.04.001. Epub 2016 Apr 14. PMID: 27091298 [PubMed – indexed for MEDLINE]
Resident CAPS on dense-core vesicles docks and primes vesicles for fusion.
Kabachinski G, Kielar-Grevstad DM, Zhang X, James DJ, Martin TF. Mol Biol Cell. 2016 Feb 15;27(4):654-68. doi: 10.1091/mbc.E15-07-0509. Epub 2015 Dec 23. PMID: 26700319 [PubMed – indexed for MEDLINE]
Topological defects in liquid crystals as templates for molecular self-assembly.
Wang X, Miller DS, Bukusoglu E, de Pablo JJ, Abbott NL. Nat Mater. 2016 Jan;15(1):106-12. Epub 2015 Sep 21. doi: 10.1038/nmat4421. PMID: 26390324
2015
Anionic Phospholipids Stabilize RecA Filament Bundles in Escherichia coli.
Rajendram M, Zhang L, Reynolds BJ, Auer GK, Tuson HH, Ngo KV, Cox MM, Yethiraj A, Cui Q, Weibel DB. Mol Cell. 2015 Nov 5;60(3):374-84. Epub 2015 Oct 17. doi: 10.1016/j.molcel.2015.09.009. PMID: 26481664
2014
FOLFOX/FOLFIRI pharmacogenetics: the call for a personalized approach in colorectal cancer therapy.
Mohelnikova-Duchonova B, Melichar B, Soucek P. World J Gastroenterol. 2014 Aug 14;20(30):10316-30. doi: 10.3748/wjg.v20.i30.10316. PMID: 25132748